As with all inhaled medication containing corticosteroids, the drug Seretide Multidisk should be used with caution in patients with acute or latent pulmonary tuberculosis.
The drug Seretide Multidisk be used with caution in thyrotoxicosis.
The drug Seretide Multidisk should be used with caution in fungal, viral or bacterial infections respiratory.
Upon receipt of any group sympathomimetic drugs, particularly when exceeding the therapeutic dose, such possible development of cardiovascular events such as increase in systolic blood pressure and heart rate. For this reason, drug Seretide Multidisk should be used with caution in patients with cardiovascular diseases, including arrhythmias such as supraventricular tachycardia and premature beats, ventricular premature beats, atrial fibrillation.
All sympathomimetic drugs in doses exceeding therapeutic, may cause a transient decrease in potassium level in serum. Therefore, drug deca durabolin pills should be used with caution in patients with hypokalemia.
Seretid Multidisk drug should be used with caution in patients with an allergic reaction to milk protein and lactose history as residual amounts of the protein may be part of lactose.
Any inhaled corticosteroids may cause systemic effects, especially with prolonged use at high doses. Therefore, the drug should be used with caution in glaucoma, cataracts, osteoporosis (see. Section “Special instructions and precautions for use”).
There are very rare reports of increased blood glucose levels, so diabetics should use the drug Seretide Multidisk with caution (see. “Side effects” section).
Pregnancy and lactation
Pregnant women and lactating women should be prescribed only if the expected benefit to the mother outweighs any possible risk to the fetus or child. Insufficient data on the use of salmeterol and fluticasone propionate during pregnancy and lactation.
Reproductive toxicity of the drug and its components was studied during preclinical studies. Excessive concentration of active systemic beta 2 -adrenomimetika and deca durabolin pills has effects on the fetus.
Extensive clinical experience with this class of drugs shows that when using therapeutic doses of these effects are not clinically significant. Salmeterol and fluticasone propionate have no genotoxicity.
The concentration of salmeterol and fluticasone propionate in plasma after inhalation of the drug in therapeutic doses is extremely low, so the concentration in human milk should be as low. This is supported by studies in animals in which the milk was measured low concentrations of salmeterol and fluticasone propionate. No data on concentrations of salmeterol and fluticasone propionate in the breast milk of women during breastfeeding.
Dosage and administration:
Drug Seretide Multidisk is intended only for inhalation.
The patient should be informed that in order to achieve optimal effect the drug should be used regularly, even in the absence of clinical symptoms of asthma.
The doctor should regularly assess the effectiveness of patient treatment.
Determination of the duration of therapy and dose modification preparation is possible only on doctor’s advice.
Dose should be reduced to the lowest dose that provides effective control of symptoms.
If the a day provides symptom control, as part of reducing the dose to the lowest possible effective reduction in the frequency of dosing to 1 times per day.
The patient should be given a form of the drug deca durabolin pills, which contains a dose of fluticasone propionate, the corresponding severity of the disease. If treatment with inhaled corticosteroids do not provide adequate control of the disease, they are replacing the drug at a dose of Seretide Multidisk therapeutically equivalent dose administered corticosteroids may improve the control of bronchial asthma.Patients who can control only for asthma using inhaled corticosteroids and their replacement drug Seretid Multidisk may allow to reduce the dose corticosteroids necessary for control of asthma.
Adults and children 12 years and older
One inhalation (50 micrograms salmeterol and 100 micrograms fluticasone propionate), 2 times a day,
another inhalation (50 micrograms salmeterol and 250 micrograms fluticasone propionate), 2 times a day,
another inhalation (50 micrograms salmeterol and 500 micrograms of fluticasone propionate), 2 times a day.
Children 4 years and older
One inhalation (50 mcg salmeterol and 100 mcg fluticasone propionate) 2 times a day.
There is currently no data on the use of the drug Seretide Multidisk in children up to 4 years.
Chronic obstructive pulmonary disease (COPD)
For adult patients, the maximum recommended dose is 1 inhalation (50 mcg salmeterol and 500 mcg fluticasone propionate) 2 times a day.For this dosage of the drug Seretide Multidisk has been demonstrated a reduction in mortality from any cause.
After using the inhaler, rinse your mouth with water and then spit it.
Keep the deca durabolin pills inhaler dry.
Keep it closed when not in use.
You can never do exhale into the inhaler.
Turn the lever only at the moment when you are ready to receive a dose.
Do not exceed the prescribed dose. Hold the inhaler out of the reach of children.