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Sertraline is bound to plasma proteins. It is therefore necessary to consider the possibility of interaction with other drugs that bind to the protein (eg, diazepam, tolbutamide and warfarin). Cimetidine:simultaneous use significantly reduces the clearance of sertraline. Drugs metabolized isoenzyme cytochrome : long-term treatment with sertraline 50 mg per day accompanied by increased concentrations of …

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In elderly patients there is no need for a special selection of doses. Patients with impaired hepatic function require special attention in the treatment of sertraline. In severe liver function disorder the dose should be reduced dose or increase the interval between receptions. In patients with impaired renal function deca durabolindeca durabolin┬áspecially select a dose …

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Absorption of sertraline from the gastrointestinal tract significantly, but is slow. Maximum plasma concentration is achieved through 4,5-8,4 hours after ingestion of the drug. The equilibrium concentration of sertraline in blood plasma is achieved within a week for a single daily reception. Bioavailability during meal increased by 25%, the time to maximum concentration is shortened. …

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On the part of the immune system : hypersensitivity reactions: sometimes – rash, very rarely – anaphylactic reactions, including edema and angioedema, bronchospasm, anaphylactic shock. On the part of metabolism : rarely – hyperglycemia, hypokalemia. From what is deca durabolinwhat is deca durabolin┬áthe nervous system :. often – tremor, headache These adverse events are often …